Late 90s hip hop song, guitar sample, 5 notes repeating

delicious_oil

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I'm thinking of a popular summer hip hop song from the late 90s or early 2000s, with a 5-note guitar sample that repeats a few times throughout the song. There is at least one male rapper, and possibly a female rapper. The guitar part is really catchy and upbeat, instantly recognizable. I can only describe the chord progression as up-down-up-up-down. It's still frequently played in dance clubs. Any idea what this is?
 

delicious_oil

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It may have been a synthesizer that did the 5 notes. Surely someone must know what this is?
 
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